Before using Avana for heart health, individuals should be aware of potential interactions with other medications and the possibility of side effects. Avana can interact with certain drugs, including nitro-glycerine, alpha-blockers, and antihypertensive medications, leading to adverse effects or worsening of heart conditions. It's essential to inform healthcare providers about all medications, supplements, and underlying health conditions to minimize the risk of complications. Common side effects of Avana include headache, flushing, nasal congestion, and gastrointestinal discomfort. While these side effects are usually mild and temporary, individuals experiencing severe or persistent symptoms should seek medical attention promptly. Healthcare providers can adjust dosage or recommend alternative treatments to manage side effects effectively.