Tapentadol 200mg can be prescribed for knee pain, particularly when the pain is moderate to severe. This dosage typically targets chronic pain or conditions such as osteoarthritis or other joint issues. Tapentadol works through a dual-action mechanism: it both inhibits the reuptake of norepinephrine and binds to opioid receptors, providing effective relief. However, its use should be under strict medical supervision due to potential side effects such as dizziness, nausea, or the risk of dependency.