Cenforce 25 mg should be used with caution in special populations such as older adults and individuals with hepatic or renal impairment. Dosage adjustments may be necessary in these populations to minimize the risk of adverse effects. Priapism, a rare but serious side effect of sildenafil citrate, requires immediate medical attention to prevent tissue damage and permanent erectile dysfunction. If you experience a prolonged erection lasting more than four hours, seek emergency medical care.