Before starting Silditop 100, it's advisable to consult a healthcare professional who can assess your medical history and determine if it is suitable for you. The recommended starting dose of Silditop 100 is 50 milligrams, taken approximately one hour before sexual activity. However, the dosage may be adjusted based on individual response and tolerance, as advised by your healthcare provider. Grapefruit and alcohol can interact with Silditop 100 and potentially increase the risk of side effects. It's best to avoid consuming them while using this medication.